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8. The SNMMI and EANM practice guideline for renal scintigraphy in adults Eur J Nucl Med Mol Imaging. 2018 Nov;45(12):2218-2228. doi: 10.1007/s00259-018-4129-6. Piepsz A, Colarinha P, Gordon I, et al. Guidelines for 99mTc-DMSA scintigraphy in children. Eur J Nucl Med. 2001;28(3):BP37–41.
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The European procedure guidelines for Tc-99m-DMSA renal scintigraphy were initially published in 2001 and updated in 2011, whereas similar NA guidelines were initially published in 1997 and DMSA scintigraphy is indicated in children for evaluation and/or detection of acute pyelonephritis, renal scars, small kidneys, duplicated collecting systems, renal masses and systemic hypertension . 99m Tc DMSA is a renal cortical scanning agent that localizes in the proximal tubules. Guidelines. Providing the community with up-to-date guidelines is one of the core activities of the EANM under the lead of its Committees. Browse this section for the most recent EANM-led and EANM-endorsed publications. Questions or comments related to the EANM guidelines are welcome any time via guidelines@eanm.org. The SNMMI and EANM Practice Guideline for Renal Scintigraphy in Adults: June 22, 2018: The SNMMI and EANM Procedural Guidelines for Diuresis Renography in Infants and Children: January 27, 2018: SNMMI Procedure Standard/EANM Practice Guideline for Diuretic Renal Scintigraphy in Adults With Suspected Upper Urinary Tract Obstruction 1.0: October 1, 2010 99mTc-dimercaptosuccinic acid (DMSA) scintigraphy is currently the method of choice for assessing renal scarring in children, but it is not established whether conducting the scan as a single photon emission tomography combined with low-dose CT (SPECT/ldCT) scan provides additional diagnostic benefits when compared to conventional planar scintigraphy.
In most centres scintigraphy is generally performed 2-4 hours after DMSA administration. 1.2.3 Sensitivity for renal lesions Studies in animals show that static renal scintigraphy with DMSA is the most sensitive imaging method to identify parenchymal lesions (Rushton et EANM Procedure Guidelines for 99m Tc-DMSA Scintigraphy in Children (2009) The purpose of this guideline is to offer to the nuclear medicine team a framework that could prove helpful in daily practice.
Infants with urinary tract infection - renal - AVHANDLINGAR.SE
7. The minimal administered activity for 99mTc-DMSA is ~11 MBq (0.3 mCi).
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Although 99m Tc-dimercaptosuccinic acid (DMSA) scintigraphy is widely considered the method of choice for detecting renal cortical scarring in children, notably after pyelonephritis [1,2], currently, conventional planar scintigraphy rather than single photon emission tomography combined with low-dose CT (SPECT/ldCT) is recommended . However, the sensitivity of DMSA scan for acute pyelonephritis may be as low as 46%. Procedure: Patient is injected with 2-5 mCi of Technetium-99m DMSA intravenously and static imaging is done using Gamma camera after 2-3 hours. Imaging time is approximately 5 - 10 minutes depending on the views take. DMSA scintigraphy was performed at a median of 10 days after the start of treatment and was abnormal in 73 children (42%), equivocal in 29 (16%) and normal in 73 (42%). Reflux was seen in 27% of all children and in 38% of the renal units that were abnormal at DMSA scintigraphy.
Structural information, however, is limited.
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concluded that, in a series of DMSA studies performed mainly during the acute and remission phases of renal infection, the overall reproducibility was excellent among a large number of nuclear medicine physicians. 2020-08-04 DMSA scintigraphy is nowadays recommended as the technique of choice for evaluation of renal sequelae; 6 months seem to be an acceptable delay after acute infection in order to be able to consider the DMSA abnormalities as permanent sequelae. The situation is less clear in the case of acute pyelonephritis (the so-called “acute” DMSA). Renal Cortical Scintigraphy (DMSA scan) Clinical Guidelines 1.
7. The minimal administered activity for 99mTc-DMSA is ~11 MBq (0.3 mCi). The maximum administered activity for 99mTc-DMSA is ~110 MBq (3.0 mCi). 8. Recently, the European Association of Nuclear Medicine revised its guidelines for the use of [99m Tc]-(V)DMSA scintigraphy in children.
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Eur J Nucl Med 2001 28(3):BP37-41. • Piepsz A and Han HR. 99mTc-dimercaptosuccinic acid (DMSA) scintigraphy is currently the method of choice for assessing renal scarring in children, but it is not established whether conducting the scan as a single photon emission tomography combined with low-dose CT (SPECT/ldCT) scan provides additional diagnostic benefits when compared to conventional planar scintigraphy. CONCLUSIONS: Although 99mTc-DMSA renal scan can be carried out using the guidelines' recommended dose with conventional image acquisition time in patients weighing 20 kg or more, those < 20 kg need consideration for a longer image acquisition time to obtain diagnosable images. PMID: 30484259 [Indexed for MEDLINE] MeSH terms. Adolescent; Body Weight 2016-09-21 2019-08-07 2018-08-30 2000-01-01 The dose of renal scintigraphy with Tc-99m-DMSA in children aged 1-15 years varies between 0.68 to 1.22 mSV (depending on guidelines used), whereas the effective radiation dose from plain chest radiography in neonates and pediatric patients varies from 0.016 to 0.02 mSv [7,8]. Background: Performing micturiting cystourethrography (MCUG) in young children with recurrent urinary tract infections is controversial with discrepancy among the major guidelines. Objective: Previous studies have shown that a normal dimercaptosuccinic acid (DMSA) scintigraphy may avoid the need of performing MCUG for detecting vesicoureteric reflux in children with first febrile urinary tract infection.
2018-11-27 · The estimated CVs from groups 1 and 2 with weight < 20 kg exceeded 19.9%. Although 99mTc-DMSA renal scan can be carried out using the guidelines’ recommended dose with conventional image acquisition time in patients weighing 20 kg or more, those < 20 kg need consideration for a longer image acquisition time to obtain diagnosable images.
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The purpose of the study was to determine the appropriate • Piepsz A, Blaufox MD, Gordon I, et al. Consensus on renal cortical scintigraphy in children with urinary tract infection. Semin Nucl Med 1999 29(2):160-74.