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Methods: The right knee in 12 asymptomatic volunteers was examined using a 3D Look-Locker sequence on two occasions after an intravenous injection of a double or triple dose of Gd-DTPA2-(0.2 or 0.3 mmol/kg body weight). The relaxation time (T 1) and relaxation rate (R 1 =1/T sequences using a 3T MRI scanner (Magnetom Skyra, Siemens) and a dedicated 16-channel hand coil. Images were analyzed by two independent raters for dGEMRIC indices, PsA MRI scores (PsAMRIS), and All MR imaging was performed on a 3T MR scanner (MAGNETOM Skyra, Siemens Healthcare, Erlangen, Germany) with a 15-channel Tx/Rx knee coil. Axial and sagittal PD-weighted images with fat saturation, and T1-weighted 3D VIBE images were acquired for morphological analysis. Introduction. Delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) and contrast-enhanced computed tomography (CECT) have been proposed for diagnostics of proteoglycan loss in osteoarthritis (OA).

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The relaxation time (T 1) and relaxation rate (R 1 =1/T Specialistična bolnica je opremljena z najsodobnejšim aparatom znamke Siemens – MAGNETOM Avanto, A Tim System, z jakostjo magnetnega polja 1.5 T z visoko kvaliteto slike in z možnostjo snemanja z izjemno veliko hitrostjo. dGEMRIC – diagnosticiranja obrabe hrustanca. MR preiskava, ki omogoča specifično diagnosticiranje zgodnje obrabe Background The dGEMRIC (delayed Gadolinium-Enhanced MRI of Cartilage) technique has been used in numerous studies for quantitative in vivo evaluation of the relative glycosaminoglycan (GAG) content in cartilage. The purpose of this study was to determine the influence of pre-contrast T1 and cartilage thickness when assessing knee joint cartilage quality with dGEMRIC. Methods Cartilage The dGEMRIC method used in our study, and that was based on a dual–flip-angle technique, is sensitive to B 1 inhomogeneities, which are even worse at higher field strengths.

MR examinations were performed on a Siemens 1.5 T system (Magnetom Avanto, Siemens, Erlangen,Germany) and a body matrix phased array coil. The dGEMRIC scans were obtained after a double dose (0.4 mL/kg) intravenous injection of FDA approved The MRI imaging was performed using a 1.5 T Siemens Avanto MRI machine (Siemens Healthcare GmbH, Erlangen, Germany).

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MR imaging protocol Siemens Magnetom Trio 3.0 Tesla (T) magnets (Siemens AG, Erlangen, Germany) were used at three of the seven study sites, two sites used Signa Excite/Genesis 3.0 T … Interestingly, when we compared results from our previously published article assessing the one year effect after intra-articular injection of autologous microfragmented adipose tissue, where out of 331 dGEMRIC measurements, 175 measurements (82.6%) were showing changes with a greater magnitude than 15%, while the remaining 37 dGEMRIC measurements (17.5%) were showing relevant decrease, it Objective: To prospectively compare chemical-exchange saturation-transfer (CEST) with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) and T2 mapping to assess the biochemical cartilage properties of the knee. Method: Sixty-nine subjects were prospectively included (median age, 42 years; male/female = 32/37) in three cohorts: 10 healthy volunteers, 40 patients with clinically suspected This definition approximates grade 2 knee OA based on the Kellgren and Lawrence scale 36 . MRISubjects were investigated with dGEMRIC 20.6 years (mean; range 18e23) after the injury, using a standard 1.5 T MRI system with a dedicated knee coil (Magnetom Vision; Siemens Medical Solutions, Erlangen, Germany).

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Delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) is an imaging method for detecting early damage to cartilage. Furthermore, we defined dGEMRIC and T map- (Siemens Healthcare), which provides the protocols and inline cal- ping reference values for healthy and diseased cartilage of culation of parametric maps of T and T properties of the imaged 1 2 the wrist at 3T. tissue and automatically generates parametric color-coded maps. Thirteen knee imaging studies were performed on a 3 Tesla Siemens TIM Trio scanner (Siemens Medical Solutions, Erlangen, Germany) using a single channel transmit-receive extremity coil. A complete quantitative cartilage imaging study (T1ρ, T2 and dGEMRIC) was collected in two sessions within a four hour period ( Figure 1 ). The mean dGEMRIC indices for DDH and FAI were 531 ± 92.7 (391–729) ms and 551 ± 95.7 (372–694) ms, respectively (P = 0.507).

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Rationale and Objectives. The objectives of this study were to measure the parallel changes of transverse relaxation times (T 2), spin-lattice relaxation time in the rotating frame (T 1ρ), and the delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC)-T 1 mapping of human knee cartilage in detecting cartilage degeneration at 3.0T. Siemens Healthcare | 12/01/2008 The articles and case reports in this issue of MAGNETOM Flash are proof of the broad spectrum of examinations that are supported or even enabled by Tim®– the Total imaging matrix.
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dGEMRIC was performed on a 1.5T Siemens Symphony magnet . Each subject recieved 0.2 mmol/kg of Gd(DTPA) 2 (Magnevist®, Bayer Healthcare) contrast agent, followed by a saline flush. Immediately after contrast administration , each subject walked for 10 minutes to promote diffusion of the contrast into synovial fluid and cartilage. dGEMRIC images were analyzed by an experienced musculoskeletal radiologist using the syngoMaplt software (Siemens). The dGEMRIC index was analyzed on seven di erent articular facets: the medial and lateral femoral condyle, femoral trochlea, medial and lateral tibial condyle and both patellar facets, before dGEMRIC, on demographic and KL grade data or on knee alignment data were excluded from the analysis (figure 1). MR imaging protocol Siemens Magnetom Trio 3.0 Tesla (T) magnets (Siemens AG, Erlangen, Germany) were used at three of the seven study sites, two sites used Signa Excite/Genesis 3.0 T MRI long-bore MR examinations were performed on a Siemens 1.5 T system (Magnetom Avanto, Siemens, Erlangen, Germany) and a body matrix phased array coil. The dGEMRIC scans were obtained after a double dose (0.4 mL/kg) intravenous injection of FDA approved contrast agent Magnevist (Gd-DTPA2; Berlex Laboratories, Wayne, NJ). Patients were The MRI imaging was performed using a 1.5 T Siemens Avanto MRI machine (Siemens Healthcare GmbH, Erlangen, Germany).

Patients received 0.2 mg/kg Gd(DTPA) 2− (Magnevist ® , Schering AG, Berlin, Germany) intravenously, followed by a 10 min timed walk. dGEMRIC imaging was performed 60 min after the injection. The Siemens South Africa head office in Johannesburg has implemented a Distributed Energy System (DES) as a solution to tackle Africa’s energy transition. Th This definition approximates grade 2 knee OA based on the Kellgren and Lawrence scale 36 . MRISubjects were investigated with dGEMRIC 20.6 years (mean; range 18e23) after the injury, using a standard 1.5 T MRI system with a dedicated knee coil (Magnetom Vision; Siemens Medical Solutions, Erlangen, Germany).
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MR preiskava, ki omogoča specifično diagnosticiranje zgodnje obrabe Background The dGEMRIC (delayed Gadolinium-Enhanced MRI of Cartilage) technique has been used in numerous studies for quantitative in vivo evaluation of the relative glycosaminoglycan (GAG) content in cartilage. The purpose of this study was to determine the influence of pre-contrast T1 and cartilage thickness when assessing knee joint cartilage quality with dGEMRIC. Methods Cartilage The dGEMRIC method used in our study, and that was based on a dual–flip-angle technique, is sensitive to B 1 inhomogeneities, which are even worse at higher field strengths. Therefore, we performed dGEMRIC only at 3 T. Another limitation is the relatively long interval between dGEMRIC and sodium imaging examinations. In dGEMRIC, at the tibial plateau, the OA cartilage showed a higher change in the relaxation rate than intact cartilage. In addition, in delayed CT arthrography the contrast agent partition (Fig.

Of these techniques, only dGEMRIC has so far become clinically use-ful in cartilage repair imaging.
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BACKGROUND: Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is a validated technique for evaluating cartilage health in developmental dysplasia of the hip (DDH), which can be a helpful prognosticator for the response to surgical treatments. dGEMRIC requires intravenous injection of gadolinium contrast, however, which adds time, expense, and possible adverse reactions to the … Delayed Gadolinium Enhanced MRI of Cartilage (dGEMRIC) in Hip Dysplasia Marcel Dudda, M.D.; et al. Dept. of Orthopaedic Surgery, Children’s Hospital Boston, Harvard Medical School, Boston, USA Clinical Application of delayed Gadolinum Enhanded MRI of Cartilage (dGEMRIC) Marcel Dudda, M.D.; Young Jo Kim, M.D., Ph.D. | 2009-07-13 MAGNETOM Marketing Tool Kit Twenty six hips in 16 patients were scanned (14 left hips, 12 right hips).